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Sermorelin
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TB-500
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Sermorelin

Original price was: $85.00.Current price is: $59.50.

Sermorelin is the 29-amino-acid, C-terminally amidated N-terminal fragment of human growth-hormone–releasing hormone (GHRH(1-29)-NH₂). It is a selective agonist of the GHRH receptor (GHRHR) on pituitary somatotrophs and is used as a research tool to study hypothalamic-pituitary GH axis dynamics and downstream IGF-1 signaling. 

Description

Product details

Amino Acid Sequence

Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-NH₂

Molecular Formula:

C₁₄₉H₂₄₆N₄₄O₄₂S

Molecular Weight:

3357.9 g/mol

PubChem CID:

16132413

CAS Number:

86168-78-7

Vial Size:

3 mL

Contents:

Lyophilized powder, white/off-white color

Mechanism of action

GHRH Receptor Agonism & GH Release

Sermorelin binds to GHRH receptors on pituitary somatotrophs, stimulating cAMP/PKA signaling and promoting both GH secretion and GH gene transcription.

IGF-1 Axis Activation

Released GH acts on the liver and peripheral tissues to increase IGF-1 production, which drives anabolic, lipolytic, and osteoanabolic effects.

Selective Pituitary Action

GHRH receptor distribution is concentrated in somatotrophs, giving sermorelin selectivity for GH release without significant effects on other pituitary hormones.

Storage & handling

Storage:

Store the lyophilized vial in a cool, dry area protected from direct sunlight.
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All products on this site are for research and development, laboratory, or analytical use only; they are not for human consumption, medical, diagnostic, cosmetic, veterinary, or any other non-research application. The statements and products have not been evaluated by the U.S. Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent any disease. Honest Peptide is not a compounding pharmacy or chemical compounding facility as defined under section 503A of the Federal Food, Drug, and Cosmetic Act, nor an outsourcing facility as defined under section 503B.

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